Credelio Quattro™ is the broadest* parasite protection available in an isoxazoline endectocide. Unlike other endectocides, Credelio Quattro protects against six types of parasites in one monthly flavored chewable tablet.
*Based on label comparison of the number of parasite types covered in an isoxazoline endectocide for dogs




*Based on label comparison of the number of parasite types covered in an isoxazoline endectocide for dogs
§Amblyomma americanum (lone star tick)
¶Based on the time to statistical significance vs. control in a study comparing Credelio® (lotilaner)—not Credelio Quattro™, which contains lotilaner as well as moxidectin, praziquantel, and pyrantel — to the active ingredients in Simparica Trio® (sarolaner, moxidectin, and pyrantel) and NexGard® (afoxolaner).

In a study1, lotilaner was shown to inhibit the neuromuscular function of ticks§ in just 2 hours.

In flea infested homes, just 3 monthly doses of lotilaner reduced flea populations by 99.5-100%.
Time point at which each active ingredient achieved consistent superior efficacy versus untreated control group (P ≤ 0.05)
1Reif KE,Kollasch TM,Neilson JC, et al. Comparative speed of kill provided by lotilaner(Credelio™), sarolaner (Simparica Trio™), and afoxolaner (NexGard™) to control Amblyomma americanum infestations on dogs. Parasit Vectors. 2024;17(1):313.
Lotilaner reaches peak absorption in only 2 hours and maintains high, sustained blood levels for the entire month.2,3

Dipylidium caninum can be diagnosed by their shedding of large, visible proglottids. Adult tapeworms range from 15-70 cm.7

Echinococcus are difficult to diagnose due to their small size and low number of body segments. E. granulosus grow to just 2-7 mm.8
Tapeworms don’t just threaten dogs: they can be passed from dogs to humans. CAPC recommends monthly deworming of dogs with praziquantel in areas where E. granulosus tapeworms are endemic.7,8
A single monthly dose of Credelio Quattro has been shown to be 100% efficacious against tapeworms# in dogs with its industry-established dose of praziquantel (2.28mg/lb).
#Echinococcus granulosus, Dipylidium canium, and Taenia pisiformis
Eagle Animal Hospital is dedicated to providing compassionate, high-quality pet healthcare.
Paws & Care Veterinary Clinic is dedicated to providing compassionate, high-quality pet healthcare.
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